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Deep tech diagnostics for the AI-driven era
⭐ WELCOME TO THE FUTURE

Guanine: Healthcare Reimagined

A software-defined electrochemical sensing architecture for the intelligence-driven era of healthcare.

Guanine is building a software-defined electrochemical sensing architecture for multi-omic diagnostics and real-time phenotyping.

Multiplexing, target identity, and scale are defined in software—not constrained by optics or biology-specific hardware. This transforms electrochemistry into a programmable sensing layer that can be reconfigured across biology, applications, and workflows without redesigning the core system.

One sensing architecture measures across nucleic acids, proteins, metabolites, cells, and redox biology—enabling high-plex, quantitative measurement and functional readouts without optics, PCR, or complex instrumentation.

Proven first in sepsis, the architecture enables time-aligned clinical insight across the decision window: rapid host response, broad pathogen ID/AMR, and culture-free phenotyping.

One infrastructure. Many diagnostic configurations—for hospitals and OEM innovators.
NEW WHITE PAPER
Sepsis Diagnosis at the Speed of Clinical Decision

Time-aligned diagnostics delivering actionable insight across the first critical hours of sepsis.

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Sepsis white paper cover preview
⭐ THE HEALTHCARE PROBLEM

Diagnostics Has Reached Its Limits

Healthcare depends on aging diagnostic technologies—PCR, immunoassays, sequencing, LC/MS, flow cytometry, and culture—that are fragmented, slow, expensive, and difficult to unify.

  • Data arrives too late and too narrow to guide time-critical decisions
  • Multi-omic measurement requires multiple instruments and workflows
  • High-plex quantitative testing is constrained by hardware-defined architectures
  • Hospitals face pressure to decentralize testing while improving speed and quality
  • OEMs lack a scalable sensing layer to rehost proprietary biomarkers at low cost
The result: delayed decisions, higher costs, and preventable patient harm.
⭐ GUANINE’S BREAKTHROUGH SOLUTION

A Software-Defined Electrochemical Sensing Architecture

Guanine transforms electrochemistry into a unified sensing layer in which multiplexing and target identity are configured in software—not fixed by optics or biology-specific hardware.

  • Measure nucleic acids, proteins, metabolites, cells, and redox biology from one sample
  • High-plex quantitative measurement enabled by software-derived signal separation
  • Rapid clinical workflows: 20-minute host response, 60-minute pathogen ID/AMR, 90-minute phenotyping
  • OEM-ready configurations across pharma, oncology, neurology, cardiology, and high-plex diagnostics
  • Low-capital, scalable architecture—no optics, pumps, or thermal cycling required
Guanine replaces fragmented diagnostic stacks with a single, software-defined sensing infrastructure. “One Architecture. Many Configurations.”
⭐ DEEP TECH DX

Electrochemical Deep Tech for the Next Generation of Diagnostics

Guanine unifies reversible quadruplex tags, multi-domain waveform control, magnetic concentration, and composite multiplex encoding into a single electrochemical engine—built for quantitative, high-plex, AI-ready diagnostics.

One sensing architecture. Multiple diagnostic modes.
Culture-free phenotyping

Culture-Free Phenotyping

Functional antibiotic response readouts within the clinical decision window—without culture-based AST delays.

Multi-omic in one run

Multi-Omic in One Run

Nucleic acids, proteins, metabolites, cells, and redox biology measured from the same sample.

Architecture for OEM innovators

Architecture for OEM Innovators

A software-defined sensing layer that enables new assay configurations without redesigning core hardware.

⭐ WHY NOW

The Diagnostic Landscape Has Shifted—Permanently

Clinical Drivers
  • Sepsis and AMR require rapid, actionable data
  • Drug susceptibility must move beyond culture
  • Clinicians need integrated host–pathogen insight
Economic Drivers
  • Hospitals face severe cost and staffing pressures
  • Diagnostics must move closer to the patient
OEM & Technology Drivers
  • Optical systems are hitting hard multiplexing limits
  • AI requires high-plex, quantitative multi-omic data
  • OEMs want faster, lower-capital paths to new assay menus
Guanine is a software-defined sensing architecture designed for this reality.
Explore how Guanine is transforming sepsis care and enabling OEM innovators to scale through new configurations.
Explore Guanine's technology See our sepsis solutions View OEM platforms