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Software-defined electrochemical waveforms with encoded signal separation motifs
⭐ A New Detection Standard

A Software-Defined Electrochemical Biosensing Architecture

Target identity, quantification, multiplexing, and scale are defined in software —
not optics or biology-specific hardware.

Guanine is building a new category of diagnostic infrastructure: a software-defined electrochemical sensing architecture for multi-omic diagnostics and real-time phenotyping. By transforming electrochemistry into a programmable sensing layer, the platform can be reconfigured across biology, applications, and workflows—without redesigning the core system.

One sensing architecture measures nucleic acids, proteins, metabolites, drugs, cells, and redox biology from a single engine—enabling high-plex, quantitative measurement and functional readouts without optics, PCR, or complex instrumentation.

By decoupling diagnostic capability from optics, channels, and modality-specific instruments, Guanine enables a low-cost sensing engine to scale across applications—from time-critical sepsis care to OEM diagnostic platforms.

One sensing architecture. Unlimited biology.
NEW WHITE PAPER
Sepsis Diagnosis at the Speed of Clinical Decision

Time-aligned diagnostics delivering actionable insight across the first critical hours of sepsis.

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Sepsis white paper cover preview
⭐ Why This Matters

Why Diagnostics Has Reached Its Limits

Healthcare still relies on siloed diagnostic stacks—PCR, immunoassays, sequencing, mass spectrometry, and culture—that are difficult to unify.

  • Each biological domain requires a different instrument and workflow
  • Multiplexing is constrained by optics, channels, and spectral overlap
  • Low-concentration biomarkers demand costly, slow infrastructure
  • AI and precision medicine are starved for rich, quantitative data
The limitation isn’t biology — it’s architecture.
⭐ The Consequence

Fragmented stacks. Slow answers. Narrow data.

Diagnostics remain split across modality-specific instruments and workflows, forcing serial testing and limiting data density—especially when timing, cost, and scale matter most.

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⭐ What Guanine Changes

Redefining Diagnostics at the Architecture Layer

  • Multiplexing depth is software-encoded, not hardware-limited
  • Target identity is defined algorithmically, not by instrument design
  • One electrochemical engine replaces multiple diagnostic technologies
  • Enables rapid, multi-omic, high-plex measurement at low cost
Explore the architecture powering Guanine’s technology
⭐ What This Enables

One engine. Many workflows.

A single sensing layer can be reconfigured across assays and applications—supporting time-critical clinical decisions, OEM rehosting, and data generation for AI-driven health without rebuilding optical stacks, lasers, or modality-specific instrument infrastructure.

Infrastructure economics: scale becomes a software problem—not a hardware rebuild.
⭐ DEEP TECH DX

Electrochemical Deep Tech for the Next Generation of Diagnostics

Guanine unifies reversible quadruplex tags, multi-domain waveform control, magnetic concentration, and composite multiplex encoding into a single electrochemical engine—built for quantitative, high-plex, AI-ready diagnostics.

One sensing architecture. Multiple diagnostic modes.
Culture-free phenotyping

Culture-Free Phenotyping

Functional antibiotic response readouts within the clinical decision window—without culture-based AST delays.

Multi-omic in one run

Multi-Omic in One Run

Nucleic acids, proteins, metabolites, cells, and redox biology measured from the same sample.

Architecture for OEM innovators

Architecture for OEM Innovators

A software-defined sensing layer that enables new assay configurations without redesigning core hardware.

⭐ WHY NOW

The Diagnostic Landscape Has Shifted—Permanently

Clinical Drivers
  • Sepsis and AMR require rapid, actionable data
  • Drug susceptibility must move beyond culture
  • Clinicians need integrated host–pathogen insight
Economic Drivers
  • Hospitals face severe cost and staffing pressures
  • Diagnostics must move closer to the patient
OEM & Technology Drivers
  • Optical systems are hitting hard multiplexing limits
  • AI requires high-plex, quantitative multi-omic data
  • OEMs want faster, lower-capital paths to new assay menus
Guanine is a software-defined sensing architecture designed for this reality.
Explore how Guanine is transforming sepsis care and enabling OEM innovators to scale through new configurations.
Explore Guanine's technology Sepsis as proving ground View OEM platforms