Guanine's multi-analyte multi-omics sensor offers unique capabilities including:
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Guanine's quantitative multi-analyte multi-omics sensor Guanine's sensor quantifies low concentrations by binding targets to a microparticle conjugated with millions of electroactive polyGuanine oligonucleotides. Detection targets can include nucleic acids, proteins, small molecules, cells and redox materials. |
DNA Methylation Survey
Guanine Inc is seeking feedback from epigenetic researchers, laboratory specialists and clinicians on the shortcomings of existing DNA methylation methods. Interested parties are invited to complete a survey.
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Guanine's multi-analyte multi-omics sensor is integrated into a 96-well microtiter kit or single-use point-of-care cartridge to enable target extraction, capture, purification and sandwich creation. A potentiostat generates a voltammetry scan where the oligonucleotide tags oxidize and produce electrical current. The peak electrical signal is converted to the target concentration using a pre-programmed concentration curve. The output is transmitted to an EHR system and AI algorithm.
Guanine's disruptive platform enables mobile syndromic testing at a fraction of the price of optical technologies
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Guanine's low cost quantitative mobile data can be a game changer for using AI to diagnose and treat complex illnesses
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Guanine's technology challenges the status quo
Guanine's upcoming syndromic test will quantify 32 sepsis-causing pathogens and drug resistance biomarkers, and determine antibiotic dose in 1 hour |
Sepsis detection and treatment at admission reduces hospital stays, healthcare costs and mortality to benefit doctors, hospitals and payers |
Guanine’s products can be adapted for many lucrative market applications
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Guanine's patented detection tag changes biodetection from optical to electrical Electrochemically detectable oligonucleotide tags (EC-DOTs) rich in guanine, provide a new generation of nucleic acid, protein and small molecule assays. Targets are bound to microparticles conjugated with millions of EC-DOTs. When voltage is applied a burst of electrons produces an oxidation peak proportional to the target’s concentration. This allows fast and accurate quantification. Tests include:
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Guanine has been incubated at the Mount Sinai Health System. Our predecessor company was a spin-off from NASA's Ames Research Center that commercialized NASA’s electrochemical nanosensor for detecting waterborne pathogens.